Asterixis is a type of negative myoclonus. It is a Greek word that means “not a fixed position”. Most commonly it is associated with Metabolic Encephalopathy. It was initially described as a liver flap because it was associated with hepatic encephalopathy. Not only liver failure but multiple other diseases and drugs may cause asterixis. There is a brief loss of muscle tone in agonist muscles followed by the compensatory jerk of the antagonistic muscles in asterixis. Bilateral Asterixis is most commonly associated with metabolic encephalopathy and few drugs.
Hi brainy folks, cadaver dissection is part of medical education and anatomy learning, I came across fascinating history of infamous anatomy dissection practices and made comic inspired by that. Hope you will enjoy journey of cadaver dissection. Do read cadaver criminals it is very interesting. https://www.thevintagenews.com/2018/10/06/edinburghs-most-infamous/. Dissection of human body for educational purpose was not […]
Hi brainy folks, last part of Bacillus Anthrax…hope you like it. Anthrax clinical types Cutaneous Anthrax Most common type, mode of transmission is contact with spores and its entry through breach in skin. Painless Pruritic Papule, which progresses into necrotic Black Eschar. Black eschar sloughs off in two weeks. Treatment: Combination therapy (antibiotics oral + […]
Hi Medico-Humans , Below are visual maps on Bacillus Anthrax transmission and pathogenesis, hope you enjoy reading it, Love 😍. Quick details … B. Anthrax transmission Anthrax is zoonotic illness, following are mode of transmission- Inhalation of spores Direct contact of spores to skin (through cuts or breaks) More common in people working and living […]
Hello Brainy Folks, Few general features on Anthrax Bacillus for you 😊, It is Box shaped; gram positive capsulated bacillus. It has capsule which is made up of polypeptide Polyglutamate-D and the taste of this polyglutamate is quite repulsive for macrophages. Macrophages doesn’t like to phagocytose yucky tasting capsulated bacteria. For anthrax bacteria it is […]
The Bioweapon in Envelope The Anthrax bacteria can persist for long periods of time as a spore and can be prepared in a powdered formulation, hence B. anthracis is considered as a serious biological threat, with potential use as a military or terrorist weapon. The 2001 anthrax attacks, also known as Amerithrax from its FBI case name, occurred […]
Cystinuria Autosomal recessive hereditary defect in Amino acid transporter in Renal Proximal convoluted tubules and intestine. There is impaired resorption of Cysteine, Ornithine, Lysine, Arginine (COLA), in PCT and intestine. If these amino acids are not reabsorbed, they are excreted in urine in excess. Excessive cysteine in urine can lead to recurrent precipitation of hexagonal […]
Ch 15 autosomal recessive Hexosaminidase A deficiency causing GM2 ganglioside accumulation in all tissues, but neurons and retina is affected more. Developmental delays Exaggerated Startling response to noise Cherry red spot on macula Lysosome with onion skin appearance on EM Child is born normal and symptoms start to appear around 6 months Progressively deteriorating leading […]
… … C. difficile is a spore-forming, anaerobic, Gram-positive bacillus. Spores produced by C. difficile are heat-resistant, gastric acid and biocidal cleaning products resistant and can remain viable for months on surfaces, it can survive to hospital cleaners and even solutions that are used to disinfect the hands by healthcare professionals. The ability to produce spores is […]