Anthrax Part 2

Hi Medico-Humans ,

Below are visual maps on Bacillus Anthrax transmission and pathogenesis, hope you enjoy reading it, Love 😍.

Quick details ...

B. Anthrax transmission

Anthrax is zoonotic illness, following are mode of transmission-

1. Inhalation of spores
2. Direct contact of spores to skin (through cuts or breaks)
3. More common in people working and living close to unvaccinated animals. (wool sorter’s disease and Hide porter’s disease).
4. Bioterrorism

The Exotoxin

Bacillus Anthrax secrets tri-partite Exotoxin-PEL

P- Protective antigen- this works for host cell attachment and rest of two factors enters cell after attachment.

E-Edema factor- It works by increasing cAMP and thus causing Vasodilation, edema and eschar.

L-Lethal Factor- It induces apoptosis in host macrophages.

Synergistic effect of all three causes cell death and cell function disruption.

Bacillus Anthrax must have both capsule and exotoxin to be fully virulent.