Formerly, called central pontine myelinolysis Caused by severe damage of the myelin sheath of nerve cells, primarily in the brainstem and typically the pons Due to rapid correction of hyponatremia and in liver disease. Also called “locked-in” syndrome. Shows quadriparesis, dysarthria, dysphagia and other pseudobulbar symptoms Prevention involves slow correction of hyponatremia; at a rate […]