Kidney: The dumb, energy-inefficient, workaholic

The human kidney does not have a very energy-efficient waste disposal system.

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Kidney energetically inefficient waste disposal system
Kidney energetically inefficient waste disposal system

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Kidney Consuming ATPs Like Mad
Kidney Consuming ATPs Like Mad

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First, the glomerulus filters all the sodium, nutrients, and water needed for the body and sends them to the tubular lumen.

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Kidney: glomerular filtration and sodium in tubular filtrate
Kidney: glomerular filtration and sodium in tubular filtrate

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Then, the tubular epithelium reabsorbs most of these nutrients (including sodium) and water. The reabsorption of sodium is an active process. It consumes ATPs as an energy source. The oxygen requirement of the kidney is high because of the ATP consumed in active reabsorption.

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Tubular Reabsorption: Active Sodium Reabsorption
Tubular Reabsorption: Active Sodium Reabsorption

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The oxygen demand of the proximal tubular segment and thick ascending loop of Henle is very high. This high demand makes these parts of the renal tubule vulnerable to hypoxia and acute kidney injury.

What kind of waste disposal system first throws waste along with precious nutrients and then spends loads of energy and time to bring those nutrients back in the blood. Sounds stupid and inefficient!

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Filtration and Reabsorption in the Kidney
Filtration and Reabsorption in the Kidney

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Our kidneys are not as energy-efficient as we think, but yeah, they are crazy busy. We can at least try not to burden them more by avoiding the consumption of excess salt and sugar.

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Kidney, Hypoxia, and Salty treats
Kidney, Hypoxia, and Salty treats

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Renal Hypoxia, Salty treats, and Kidney
Renal Hypoxia, Salty treats, and Kidney

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Revision for today Hydronephrosis: Dilated Pelvis and calyx - Creative Med Doses

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