Urinary Tract Obstruction: Obstructive Nephropathy

Urinary Tract Obstruction leads to impairment in the normal flow of urine → urinary stasis and increased pressure in part proximal to obstruction → increased pressure impairs renal and urinary tract functions → renal atrophy and cortical thinning. It is a common cause of acute and chronic kidney disease (obstructive nephropathy).

Early recognition and prompt treatment of urinary tract obstruction (UTO) can prevent or reverse deteriorating effects on kidney structure and function.

The urinary tract obstruction increases susceptibility to hypertension, infection, and stone formation. Chronic obstruction may lead to permanent loss of renal mass (renal atrophy) and excretory capability, it can lead to End-stage renal disease (ESRD).

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